Coppa Italia 16

 14.12.2021

Venezia–Ternana (II.) 3–1
Udinese–Crotone (II.) 4–0
Genoa–Salernitana 1–0

15.12.2021
15.00: Verona–Empoli 3-4
18.00: Cagliari–Cittadella (II.) 3-1
21.00: Fiorentina–Benevento (II.) 2-1

16.12.2921
18.00: Spezia–Lecce (II.) 0-2
21.00: Sampdoria–Torino 2-1